Nutrafutura s.r.l.

MetaGL+ is a new-generation patented compound, designed to naturally and effectively counteract hyperglycemia through agonist action on the GLP-1 receptor.

It acts directly on the expression of this receptor, increasing its effectiveness and half-life, while also improving intestinal absorption without compromising barrier integrity.

Preclinical tests conducted using Transwell® technology confirm high cell vitality, antioxidant capacity, and protection from oxidative stress, with efficient crossing of the intestinal barrier.


Action: modulation of plasma glucose and increased satiety.


Target organs: pancreas, CNS (indirect action)

Scientific Evaluation

MetaGL+ has undergone rigorous scientific testing to evaluate its effectiveness. After being metabolized by intestinal cells, the compound was tested on pancreatic cells to assess its effect on the insulin IRS-1 receptor and calcium channels involved in hormone release. This protocol allowed in vitro verification of MetaGL+’s ability to modulate circulating glucose and promote an effective insulin response.

Mechanism of Action

The action of MetaGL+ has been studied through the analysis of key markers of glucose metabolism:

  • GLP-1 receptor: increased expression and effectiveness
  • IRS-1 receptor: involved in the insulin response
  • Calcium channels: activated to facilitate insulin release

Metabolic Benefits

MetaGL+ represents an innovative and scientifically validated solution for the natural control of blood sugar and hunger, also contributing to weight management.

  • Regulation of plasma glucose
  • Increased satiety via GLP-1 pathway
  • Protection from oxidative stress and metabolic support